Myeloperoxidase Monoclonal Antibody (MPO mAb)


Myeloperoxidase (MPO) is a 150 kDa peroxidase enzyme found predominantly in neutrophil granulocytes. It consists of two light chains (15 kDa) and two variable-weight glycosylated heavy chains (60kDa) bound to a prosthetic heme group.  Myeloperoxidase plays the key role in antimicrobial oxygen-dependent activity of neutrophils.

In diagnostics it has been shown to be of use to predict myocardial infarction (Brennan et al, 2003). Unlike other established cardiac markers, such as Troponin T, CK MB and CRP, MPO levels pinpointed high risk cardiac patients in the absence of myocardial necrosis.  At the moment MPO is under consideration as one of the most promising cardiac markers.  In addition, MPO staining is important in the diagnosis of extramedullary leukemia (chloroma).

SCIPAC offer MPO antibodies with high affinity to native as well as recombinant human MPO in ELISA as well as Western Blot format.




Product:
MPO clone N4C7
 
Cat No:
BM240-N4C7
 
Specification:
Protein G purified
 
Source:
Murine cells
 
Min Pk:
100 µg
 
Presentation:
Phosphate Buffer + azide
 
Storage:
2-8°C
 
Recomended As:
Capture
 
add to myPAC Literature PDF MSDS PDF Typical Certificate of Analysis
 
Product:
MPO clone N9A3
 
Cat No:
BM240-N9A3
 
Specification:
Protein G purified
 
Source:
Murine cells
 
Min Pk:
100 µg
 
Presentation:
Phosphate Buffer + azide
 
Storage:
2-8°C
 
Recomended As:
Detection
 
add to myPAC Literature PDF MSDS PDF Typical Certificate of Analysis