Complement C3 (C3) or C3c 

The C3 component is central in both complement activation pathways, with different specific proteolytic systems cleaving it to form C3 convertase. Cleavage of C3 releases C3a and the C3b fragment which is part of the alternative C3 convertase. C3 levels can be low because of decreased synthesis or due to consumption. High C3 levels are seen in highly acute or chronic inflammation, hepatic cholestasis and during the third trimester of pregnancy. C3c has a mol wt of approx 137kDa. The common form present in plasma and used in diagnostics assays is the C3c form offered here.
Scipac’s C3c product contains the intact Beta chain and the Alpha chain without the C3dg, C3a and C3f peptides. P150-0 should be suitable for raising polyclonal antibodies to C3.


 


Also Available
Control SolutionElevated SerumPatient Samples
Other Complement proteins
C1Q
C3
C4
Product:
C3 >10% pure
 
Cat No:
P150-4
 
Specification:
>10% pure
 
Source:
Human Plasma
 
Min Pk:
10 mg
 
Presentation:
Frozen in PBS buffer
 
Storage:
<-15°C
 
add to myPAC Literature PDF MSDS PDF Typical Certificate of Analysis
 
Product:
C3, highly pure
 
Cat No:
P150-1
 
Specification:
>96% pure
 
Source:
Human Plasma
 
Min Pk:
1 mg
 
Presentation:
Lyophilised
 
Storage:
2-8°C
 
add to myPAC Literature PDF MSDS PDF Typical Certificate of Analysis
 
Product:
C3, ultra-pure
 
Cat No:
P150-0
 
Specification:
>99% pure
 
Source:
Human Plasma
 
Min Pk:
1 mg
 
Presentation:
Frozen in PBS buffer
 
Storage:
<-15°C
 
add to myPAC Literature PDF MSDS PDF Typical Certificate of Analysis